Analgesic effects and arthritic changes following intra-articular injection of diclofenac etalhyaluronate in a rat knee osteoarthritis model
Diclofenac etalhyaluronate (DF-HA) is a recently developed analgesic conjugate of diclofenac and hyaluronic acid that has analgesic and anti-inflammatory effects on acute arthritis. In this study, we investiga...
Authors: Takahito Arai, Miyako Suzuki-Narita, Jun Takeuchi, Ikuko Tajiri, Kazuhide Inage, Yuya Kawarai, Yawara Eguchi, Yasuhiro Shiga, Takashi Hozumi, Geundong Kim, Ryuto Tsuchiya, Takuma Otagiri, Tomohito Mukaihata, Takahisa Hishiya, Noriyasu Toshi, Kohei Okuyama…
Citation: BMC Musculoskeletal Disorders 2022 23:960
Content type: Research Published on: 7 November 2022
- View Full Text
- View PDF
Total knee arthroplasty according to the original knee phenotypes with kinematic alignment surgical technique—early clinical and functional outcomes
The kinematic alignment (KA) technique in total knee arthroplasty (TKA) aims to restore the native alignment of pre-disease knee joint anatomy. Determining the individualized alignment targets is crucial for p...
Authors: Cheng-En Hsu, Jen-Ting Huang, Kwok-Man Tong and Kui-Chou Huang
Citation: BMC Musculoskeletal Disorders 2020 21:839
Content type: Research article Published on: 11 December 2020
- View Full Text
- View PDF
Comparison of neuromuscular and quadriceps strengthening exercise in the treatment of varus malaligned knees with medial knee osteoarthritis: a randomised controlled trial protocol
Osteoarthritis of the knee involving predominantly the medial tibiofemoral compartment is common in older people, giving rise to pain and loss of function. Many people experience progressive worsening of the d...
Authors: Kim L Bennell, Thorlene Egerton, Tim V Wrigley, Paul W Hodges, Michael Hunt, Ewa M Roos, Mary Kyriakides, Ben Metcalf, Andrew Forbes, Eva Ageberg and Rana S Hinman
Citation: BMC Musculoskeletal Disorders 2011 12:276
Content type: Study protocol Published on: 5 December 2011
- View Full Text
- View PDF
Comparison of computer-navigated and conventional total knee arthroplasty in patients with Ranawat type-II valgus deformity: medium-term clinical and radiological results
Arthritic knees with Ranawat type-II valgus deformity present with soft tissue contracture and osseous anomalies that make total knee arthroplasty (TKA) difficult. We hypothesized that computer-navigated-TKA (...
Authors: Tsan-Wen Huang, Chien-Yin Lee, Shih-Jie Lin, Kuo-Ti Peng, Kuo-Chin Huang, Mel S Lee, Robert Wen-Wei Hsu and Wun-Jer Shen
Citation: BMC Musculoskeletal Disorders 2014 15:390
Content type: Research article Published on: 22 November 2014
- View Full Text
- View PDF
Simultaneous bilateral total knee and ankle arthroplasty as a single surgical procedure
Simultaneous osteoarthritis (OA) of the ankle joint complicates primary total knee arthroplasty (TKA). In such cases, rehabilitation of TKA is limited by debilitating ankle pain, but varus or valgus ankle arth...
Authors: Geert Pagenstert and Beat Hintermann
Citation: BMC Musculoskeletal Disorders 2011 12:233
Content type: Case report Published on: 13 October 2011
- View Full Text
- View PDF
The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint
Recent findings support a connection between mitochondrial dysfunction and activation of inflammatory pathways in articular cells. This study investigates in vivo in an acute model whether intra-articular admi...
Authors: Carlos Vaamonde-García, Jesús Loureiro, Marta N. Valcárcel-Ares, Romina R. Riveiro-Naveira, Olalla Ramil-Gómez, Laura Hermida-Carballo, Alberto Centeno, Rosa Meijide-Failde, Francisco J. Blanco and María J. López-Armada
Citation: BMC Musculoskeletal Disorders 2017 18:254
Content type: Research article Published on: 12 June 2017
- View Full Text
- View PDF
In Vivo three-dimensional kinematics of normal knees during sitting sideways on the floor
The normal knee kinematics during asymmetrical kneeling such as the sitting sideways remains unknown. This study aimed to clarify in vivo kinematics during sitting sideways of normal knees.
Authors: Kenichi Kono, Takaharu Yamazaki, Shoji Konda, Hiroshi Inui, Sakae Tanaka, Kazuomi Sugamoto and Tetsuya Tomita
Citation: BMC Musculoskeletal Disorders 2022 23:326
Content type: Research Published on: 6 April 2022
- View Full Text
- View PDF
Postoperative clinical outcomes for kinematically, restricted kinematically, or mechanically aligned total knee arthroplasty: a systematic review and network meta-analysis of randomized controlled trials
Mechanically aligned total knee arthroplasty (MATKA) is a well-established procedure. Kinematically aligned TKA (KATKA) has been proposed to restore and preserve pre-arthritic knee anatomy. However, normal kn...
Authors: Takanori Miura, Tsuneari Takahashi, Jun Watanabe, Yuki Kataoka, Ryusuke Ae, Hidetomo Saito, Katsushi Takesh*ta and Naohisa Miyakoshi
Citation: BMC Musculoskeletal Disorders 2023 24:322
Content type: Research Published on: 24 April 2023
- View Full Text
- View PDF
Self-reported knee joint instability is related to passive mechanical stiffness in medial knee osteoarthritis
Self-reported knee joint instability compromises function in individuals with medial knee osteoarthritis and may be related to impaired joint mechanics. The purpose of this study was to evaluate the relationsh...
Authors: Mark W Creaby, Tim V Wrigley, Boon-Whatt Lim, Rana S Hinman, Adam L Bryant and Kim L Bennell
Citation: BMC Musculoskeletal Disorders 2013 14:326
Content type: Research article Published on: 20 November 2013
- View Full Text
- View PDF
Validity and reliability of using photography for measuring knee range of motion: a methodological study
The clinimetric properties of knee goniometry are essential to appreciate in light of its extensive use in the orthopaedic and rehabilitative communities. Intra-observer reliability is thought to be satisfacto...
Authors: Justine M Naylor, Victoria Ko, Sam Adie, Clive Gaskin, Richard Walker, Ian A Harris and Rajat Mittal
Citation: BMC Musculoskeletal Disorders 2011 12:77
Content type: Research article Published on: 18 April 2011
- View Full Text
- View PDF
The human arthritic hip joint is a source of mesenchymal stromal cells (MSCs) with extensive multipotent differentiation potential
While multiple in vitro studies examined mesenchymal stromal cells (MSCs) derived from bone marrow or hyaline cartilage, there is little to no data about the presence of MSCs in the joint capsule or the ligame...
Authors: Mike Wagenbrenner, Tizian Heinz, Konstantin Horas, Axel Jakuscheit, Joerg Arnholdt, Marietta Herrmann, Maximilian Rudert, Boris M. Holzapfel, Andre F. Steinert and Manuel Weißenberger
Citation: BMC Musculoskeletal Disorders 2020 21:297
Content type: Research article Published on: 13 May 2020
- View Full Text
- View PDF
Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a pilot study
Specific serum biomarkers of cartilage metabolism such as cartilage oligomeric matrix protein (sCOMP) and procollagen type II C-terminal propeptide (sPIICP) as well as hyaluronan (sHA), a biomarker of synoviti...
Authors: Christos Papaneophytou, Ana Alabajos-Cea, Enrique Viosca-Herrero, Carme Calvis, Marta Costa, Andreas E. Christodoulides, Alexander Kroushovski, Alkis Lapithis, Vaia Maligianni Lapithi, Ioannis Papayiannis, Andreas Christou, Ramon Messeguer, Christoforos Giannaki and Kyriacos Felekkis
Citation: BMC Musculoskeletal Disorders 2022 23:195
Content type: Research Published on: 2 March 2022
- View Full Text
- View PDF
Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis
Pain is the principal clinical symptom of osteoarthritis (OA), and development of safe and effective analgesics for OA pain is needed. Drug development of new analgesics for OA pain is impaired by substantial ...
Authors: Asger Reinstrup Bihlet, Inger Byrjalsen, Anne-Christine Bay-Jensen, Jeppe Ragnar Andersen, Claus Christiansen, Bente Juel Riis, Ivo Valter, Morten A. Karsdal and Marc C. Hochberg
Citation: BMC Musculoskeletal Disorders 2018 19:17
Content type: Research article Published on: 17 January 2018
- View Full Text
- View PDF
The discordance between clinical and radiographic knee osteoarthritis: A systematic search and summary of the literature
Studies have suggested that the symptoms of knee osteoarthritis (OA) are rather weakly associated with radiographic findings and vice versa. Our objectives were to identify estimates of the prevalence of radio...
Authors: John Bedson and Peter R Croft
Citation: BMC Musculoskeletal Disorders 2008 9:116
Content type: Research article Published on: 2 September 2008
- View Full Text
- View PDF
Characterization of multinucleated giant cells in synovium and subchondral bone in knee osteoarthritis and rheumatoid arthritis
Multinucleated giant cells have been noticed in diverse arthritic conditions since their first description in rheumatoid synovium. However, their role in the pathogenesis of osteoarthritis (OA) or rheumatoid a...
Authors: Iván Prieto-Potin, Raquel Largo, Jorge A Roman-Blas, Gabriel Herrero-Beaumont and David A Walsh
Citation: BMC Musculoskeletal Disorders 2015 16:226
Content type: Research article Published on: 27 August 2015
- View Full Text
- View PDF
1,25-Dihydroxyvitamin D3 prevents bone loss of the secondary spongiosa in arthritic rats by an increase of bone formation and mineralization and inhibition of bone resorption
Active vitamin D metabolites have been shown to have protective effects in experimental arthritis especially when used as preventive treatment. However, because the direct effects of 1,25-dihydroxyvitamin D3 (...
Authors: Peter Oelzner, Peter K Petrow, Gunter Wolf and Rolf Bräuer
Citation: BMC Musculoskeletal Disorders 2014 15:345
Content type: Research article Published on: 14 October 2014
- View Full Text
- View PDF
Cyclooxygenase-2 inhibitor celecoxib attenuates joint contracture following immobilization in rat knees
The aim of this study is to clarify the following two points: First, whether a cyclooxygenase-2 mediated pathway is involved in the formation of immobilization-induced joint contracture and, second, the effect...
Authors: Junya Ozawa, Akinori Kaneguchi, Ryo Tanaka, Nobuhiro Kito and Hideki Moriyama
Citation: BMC Musculoskeletal Disorders 2016 17:446
Content type: Research article Published on: 24 October 2016
- View Full Text
- View PDF
Acute murine antigen-induced arthritis is not affected by disruption of osteoblastic glucocorticoid signalling
The role of endogenous glucocorticoids (GC) in the initiation and maintenance of rheumatoid arthritis (RA) remains unclear. We demonstrated previously that disruption of GC signalling in osteoblasts results in...
Authors: Cornelia M Spies, Edgar Wiebe, Jinwen Tu, Aiqing Li, Timo Gaber, Dörte Huscher, Markus J Seibel, Hong Zhou and Frank Buttgereit
Citation: BMC Musculoskeletal Disorders 2014 15:31
Content type: Research article Published on: 3 February 2014
- View Full Text
- View PDF
Intra-articular temperatures of the knee in sports – An in-vivo study of jogging and alpine skiing
Up to date, no information exists about the intra-articular temperature changes of the knee related to activity and ambient temperature.
Authors: Christoph Becher, Jan Springer, Sven Feil, Guiliano Cerulli and Hans H Paessler
Citation: BMC Musculoskeletal Disorders 2008 9:46
Content type: Research article Published on: 11 April 2008
- View Full Text
- View PDF
Tai Chi for treating knee osteoarthritis: Designing a long-term follow up randomized controlled trial
Knee Osteoarthritis (KOA) is a major cause of pain and functional impairment among elders. Currently, there are neither feasible preventive intervention strategies nor effective medical remedies for the manage...
Authors: Chenchen Wang, Christopher H Schmid, Patricia L Hibberd, Robert Kalish, Ronenn Roubenoff, Ramel Rones, Aghogho Okparavero and Timothy McAlindon
Citation: BMC Musculoskeletal Disorders 2008 9:108
Content type: Study protocol Published on: 29 July 2008
- View Full Text
- View PDF
The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis
Posterior cruciate ligament (PCL) degeneration is often seen in knee osteoarthritis (OA); however, there is no established method for its evaluation. The purpose of this study is to investigate whether the Hou...
Authors: Yoshikazu Sumida, Tomoyuki Nakasa, Masakazu Ishikawa, Atsuo Nakamae and Nobuo Adachi
Citation: BMC Musculoskeletal Disorders 2021 22:309
Content type: Research article Published on: 26 March 2021
- View Full Text
- View PDF
Extracorporeal shockwave therapy shows a number of treatment related chondroprotective effect in osteoarthritis of the knee in rats
Extracorporeal shockwave therapy (ESWT) shows chondroprotective effect in osteoarthritis of the rat knees. However, the ideal number of ESWT is unknown. This study investigated the effects of different numbers...
Authors: Ching-Jen Wang, Shan-Ling Hsu, Lin-Hsiu Weng, Yi-Chih Sun and Feng-Sheng Wang
Citation: BMC Musculoskeletal Disorders 2013 14:44
Content type: Research article Published on: 28 January 2013
- View Full Text
- View PDF
Effects of laterally wedged insoles on symptoms and disease progression in medial knee osteoarthritis: a protocol for a randomised, double-blind, placebo controlled trial
Whilst laterally wedged insoles, worn inside the shoes, are advocated as a simple, inexpensive, non-toxic self-administered intervention for knee osteoarthritis (OA), there is currently limited evidence to sup...
Authors: Kim Bennell, Kelly-Ann Bowles, Craig Payne, Flavia Cicuttini, Richard Osborne, Anthony Harris and Rana Hinman
Citation: BMC Musculoskeletal Disorders 2007 8:96
Content type: Study protocol Published on: 24 September 2007
- View Full Text
- View PDF
Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures
Contractures of the knee joint cause disability and handicap. Recovering range of motion is recognized by arthritic patients as their preference for improved health outcome secondary only to pain management. C...
Authors: Kayleigh Wong, Fangui Sun, Guy Trudel, Paola Sebastiani and Odette Laneuville
Citation: BMC Musculoskeletal Disorders 2015 16:125
Content type: Research article Published on: 26 May 2015
- View Full Text
- View PDF
Do patients care about higher flexion in total knee arthroplasty? A randomized, controlled, double-blinded trial
Little information exists to support that patients care about flexion beyond what is needed to perform activities of daily living (ADL) after Total knee arthroplasty (TKA). The purpose of this study was to inv...
Authors: Morten G Thomsen, Henrik Husted, Kristian S Otte, Gitte Holm and Anders Troelsen
Citation: BMC Musculoskeletal Disorders 2013 14:127
Content type: Research article Published on: 8 April 2013
- View Full Text
- View PDF
Internet-mediated physiotherapy and pain coping skills training for people with persistent knee pain (IMPACT – knee pain): a randomised controlled trial protocol
Persistent knee pain in people over 50years of age is often attributable to knee osteoarthritis (OA), a common joint condition that causes physical and psychological dysfunction. Exercise and pain coping skil...
Authors: Fiona Dobson, Rana S Hinman, Simon French, Christine Rini, Francis Keefe, Rachel Nelligan, J Haxby Abbott, Christina Bryant, Margaret P Staples, Andrew Dalwood and Kim L Bennell
Citation: BMC Musculoskeletal Disorders 2014 15:279
Content type: Study protocol Published on: 13 August 2014
- View Full Text
- View PDF
Modified posterior approach of the knee in patients with diffuse pigmented Villonodular synovitis: case series of a single Institution’s experience
Diffuse pigmented villonodular synovitis (DPVNS) is a challenging tumor-like disorder that mainly occurs in the anterior aspect of the knee joint. The growth may sometimes extend to the posterior knee joint. S...
Authors: Yi-Ping Wei and Shan-Wei Yang
Citation: BMC Musculoskeletal Disorders 2022 23:197
Content type: Research Published on: 3 March 2022
The Correction to this article has been published in BMC Musculoskeletal Disorders 2022 23:542
- View Full Text
- View PDF
The fabella syndrome - a rare cause of posterolateral knee pain: a review of the literature and two case reports
The purpose of this article was to evaluate the risks and benefits of non-operative treatment versus surgical excision of a fabella causing posterolateral knee pain. We performed a systematic review of literat...
Authors: Arne Driessen, Maurice Balke, Christoph Offerhaus, William James White, Sven Shafizadeh, Christoph Becher, Bertil Bouillon and Jürgen Höher
Citation: BMC Musculoskeletal Disorders 2014 15:100
Content type: Case report Published on: 26 March 2014
- View Full Text
- View PDF
Addition of telephone coaching to a physiotherapist-delivered physical activity program in people with knee osteoarthritis: A randomised controlled trial protocol
Knee osteoarthritis (OA) is one of the most common and costly chronic musculoskeletal conditions world-wide and is associated with substantial pain and disability. Many people with knee OA also experience co-m...
Authors: Kim L Bennell, Thorlene Egerton, Caroline Bills, Janette Gale, Gregory S Kolt, Stephen J Bunker, David J Hunter, Caroline A Brand, Andrew Forbes, Anthony Harris and Rana S Hinman
Citation: BMC Musculoskeletal Disorders 2012 13:246
Content type: Study protocol Published on: 11 December 2012
- View Full Text
- View PDF
A new method for evaluation of patellar height and the position of the joint line before and after total knee arthroplasty
The measurement of patellar height and restoration of the natural position of the joint line are crucial to total knee arthroplasty (TKA). However, there remains a lack of consensus on an optimal measurement m...
Authors: Hua Han and Xiaohui Zhang
Citation: BMC Musculoskeletal Disorders 2020 21:768
Content type: Research article Published on: 21 November 2020
- View Full Text
- View PDF
Knee pain trajectories over 18 months in non-Hispanic Black and non-Hispanic White adults with or at risk for knee osteoarthritis
Pain is the hallmark symptom of knee osteoarthritis (OA), and varies widely across individuals. Previous research has demonstrated both fluctuating and stable pain trajectories in knee OA using various time pe...
Authors: Alisa J. Johnson, Terrie Vasilopoulos, Staja Q. Booker, Josue Cardoso, Ellen L. Terry, Keesha Powell-Roach, Roland Staud, Daniel A. Kusko, Adriana S. Addison, David T. Redden, Burel R. Goodin, Roger B. Fillingim and Kimberly T. Sibille
Citation: BMC Musculoskeletal Disorders 2021 22:415
Content type: Research Published on: 5 May 2021
- View Full Text
- View PDF
Can metformin relieve tibiofemoral cartilage volume loss and knee symptoms in overweight knee osteoarthritis patients? Study protocol for a randomized, double-blind, and placebo-controlled trial
Osteoarthritis (OA) is the most common joint disease, and is most frequently seen in the knees. However, there is no effective therapy to relieve the progression of knee OA. Metformin is a safe, well-tolerated...
Authors: Guangfeng Ruan, Shiwen Yuan, Aiju Lou, Yingqian Mo, Yuan Qu, Dongmei Guo, Shangqi Guan, Yan Zhang, Xiaoyong Lan, Jun Luo, Yifang Mei, Hongwei Zhang, Weirong Wu, Lie Dai, Qinghong Yu, Xiaoyan Cai…
Citation: BMC Musculoskeletal Disorders 2022 23:486
Content type: Study protocol Published on: 21 May 2022
- View Full Text
- View PDF
Hip abductor strengthening in patients diagnosed with knee osteoarthritis – a systematic review and meta-analysis
Globally osteoarthritis of the knee is a leading cause of disability. Hip abductor strength and activation are essential for maintaining postural balance during transfers and are related to joint loading and p...
Authors: Dias Tina Thomas, Shruthi R, Ashish John Prabhakar, Patel Vivekbhai Dineshbhai and Charu Eapen
Citation: BMC Musculoskeletal Disorders 2022 23:622
Content type: Research Published on: 29 June 2022
- View Full Text
- View PDF
Excellent outcomes with Oxford Uni-compartmental knee arthroplasty in anteromedial osteoarthritis patients (≤60 years) at mid-term follow-up
The use of Oxford uni-compartmental knee arthroplasty (UKA) has rapidly increased worldwide,however,the relevance of younger patients for postoperative function after Oxford UKA remains unclear. The main purpo...
Authors: Zhen Li, Zhenyue Chen, Jinqiang Wei, Xianzhong Zeng, He Sun, Zehui Li and Xuewei Cao
Citation: BMC Musculoskeletal Disorders 2021 22:859
Content type: Research Published on: 8 October 2021
- View Full Text
- View PDF
Relationship between radiological grading and clinical status in knee osteoarthritis. a multicentric study
Controversy exists regarding the relationship between radiographic findings and clinical status in knee osteoarthritis. Although the surgical indication for total knee arthroplasty (TKA) should be based on pai...
Authors: Daniel Hernández-Vaquero and José Manuel Fernández-Carreira
Citation: BMC Musculoskeletal Disorders 2012 13:194
Content type: Research article Published on: 9 October 2012
- View Full Text
- View PDF
Factors affecting the quality of life after total knee arthroplasties: a prospective study
The purpose of the study is to evaluate the self-reported outcomes in the first year after primary total knee arthroplasty (TKA), and to determine factors influencing the quality of life (QoL) 6 weeks, 3, 6, a...
Authors: Ippolyti Papakostidou, Zoe H Dailiana, Theodoros Papapolychroniou, Lycurgos Liaropoulos, Elias Zintzaras, Theophilos S Karachalios and Konstantinos N Malizos
Citation: BMC Musculoskeletal Disorders 2012 13:116
Content type: Research article Published on: 29 June 2012
- View Full Text
- View PDF
The effects of hip muscle strengthening on knee load, pain, and function in people with knee osteoarthritis: a protocol for a randomised, single-blind controlled trial
Lower limb strengthening exercises are an important component of the treatment for knee osteoarthritis (OA). Strengthening the hip abductor and adductor muscles may influence joint loading and/or OA-related sy...
Authors: Kim L Bennell, Michael A Hunt, Tim V Wrigley, David J Hunter and Rana S Hinman
Citation: BMC Musculoskeletal Disorders 2007 8:121
Content type: Study protocol Published on: 7 December 2007
- View Full Text
- View PDF
Health beliefs before and after participation on an exercised-based rehabilitation programme for chronic knee pain: Doing is believing
To explore the health beliefs, experiences, treatment and expectations of people with chronic knee pain, and investigate if, how and why these change after taking part on an integrated exercise-based rehabilit...
Authors: Michael V Hurley, Nicola Walsh, Vanita Bhavnani, Nicky Britten and Fiona Stevenson
Citation: BMC Musculoskeletal Disorders 2010 11:31
Content type: Research article Published on: 11 February 2010
- View Full Text
- View PDF
Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis
The impact of anti-TNF, corticosteroid and analgesic therapy on inflammation and pain was evaluated in a novel mono-arthritic multi-flare rat Streptococcal Cell Wall (SCW) model using Etanercept, Dexamethasone...
Authors: Kalyan Chakravarthy, Robert Faltus, Gain Robinson, Raquel Sevilla, John Shin, Mark Zielstorff, Alan Byford, Erica Leccese, Michael J Caniga, SuChun Hseih, Shuli Zhang, Chi-Sung Chiu, Jie Zhang-Hoover, Lily Y Moy, Robbie L McLeod, Dana Stoffregen…
Citation: BMC Musculoskeletal Disorders 2014 15:409
Content type: Research article Published on: 4 December 2014
- View Full Text
- View PDF
A physiotherapist-delivered integrated exercise and pain coping skills training intervention for individuals with knee osteoarthritis: a randomised controlled trial protocol
Knee osteoarthritis (OA) is a prevalent chronic musculoskeletal condition with no cure. Pain is the primary symptom and results from a complex interaction between structural changes, physical impairments and p...
Authors: Kim L Bennell, Yasmin Ahamed, Christina Bryant, Gwendolen Jull, Michael A Hunt, Justin Kenardy, Andrew Forbes, Anthony Harris, Michael Nicholas, Ben Metcalf, Thorlene Egerton and Francis J Keefe
Citation: BMC Musculoskeletal Disorders 2012 13:129
Content type: Study protocol Published on: 24 July 2012
- View Full Text
- View PDF
Value of passive anterior tibial subluxation on axial MRI in identifying anterior cruciate ligament functional deficiency in patients with advanced anteromedial osteoarthritis of the knee: a case-control study
A functionally deficient anterior cruciate ligament (ACL) is considered one of the contraindications in unicompartmental knee arthroplasty (UKA). But there is still a lack of standardized and reproducible meth...
Authors: Yuzhang Tao, Siying Tang, Pei Zhao, Wenlong Yan, Aiguo Zhou and Jian Zhang
Citation: BMC Musculoskeletal Disorders 2021 22:434
Content type: Research Published on: 13 May 2021
- View Full Text
- View PDF
MR-guided focused ultrasound for the novel and innovative management of osteoarthritic knee pain
Severe knee pain associated with osteoarthritis (OA) is one of the most common and troublesome symptoms in the elderly. Recently, local bone denervation by MR-guided focused ultrasound (MRgFUS) has been demons...
Authors: Masashi Izumi, Masahiko Ikeuchi, Motohiro Kawasaki, Takahiro Ushida, Kazuo Morio, Hirofumi Namba, Thomas Graven-Nielsen, Yasuhiro Ogawa and Toshikazu Tani
Citation: BMC Musculoskeletal Disorders 2013 14:267
Content type: Technical advance Published on: 13 September 2013
- View Full Text
- View PDF
Are patients with preoperative synovitis suitable for unicompartmental knee arthroplasty? Magnetic resonance imaging evidence from a retrospective cohort study
The use of unicompartmental knee arthroplasty (UKA) in patients with preoperative synovitis is controversial. This study aimed to investigate the association between synovitis detected by magnetic resonance im...
Authors: Zhengxi Wang, Xudong Zhang, Xianzuo Zhang, Jiaxing Wang and Chen Zhu
Citation: BMC Musculoskeletal Disorders 2023 24:433
Content type: Research Published on: 30 May 2023
- View Full Text
- View PDF
Influence of a periodized circuit training protocol on intermuscular adipose tissue of patients with knee osteoarthritis: protocol for a randomized controlled trial
The objective of this study is to analyze the influence of a 14-week periodized circuit training protocol on patients with knee osteoarthritis (OA), in randomized intervention groups, on thigh intermuscular ad...
Authors: Aline Castilho de Almeida, Maria Gabriela Pedroso, Jessica Bianca Aily, Glaucia Helena Gonçalves, Carlos Marcelo Pastre and Stela Marcia Mattiello
Citation: BMC Musculoskeletal Disorders 2018 19:421
Content type: Study protocol Published on: 30 November 2018
- View Full Text
- View PDF
Assessing stability and change of four performance measures: a longitudinal study evaluating outcome following total hip and knee arthroplasty
Physical performance measures play an important role in the measurement of outcome in patients undergoing hip and knee arthroplasty. However, many of the commonly used measures lack information on their psycho...
Authors: Deborah M Kennedy, Paul W Stratford, Jean Wessel, Jeffrey D Gollish and Dianne Penney
Citation: BMC Musculoskeletal Disorders 2005 6:3
Content type: Research article Published on: 28 January 2005
- View Full Text
- View PDF
Technology versus tradition: a non-inferiority trial comparing video to face-to-face consultations with a physiotherapist for people with knee osteoarthritis. Protocol for the PEAK randomised controlled trial
Knee osteoarthritis (OA) is a global problem that causes significant pain and physical dysfunction, substantially impacting on quality of life and imposing enormous cost to the healthcare system. Exercise is p...
Authors: Rana S. Hinman, Alexander J. Kimp, Penny K. Campbell, Trevor Russell, Nadine E. Foster, Jessica Kasza, Anthony Harris and Kim L. Bennell
Citation: BMC Musculoskeletal Disorders 2020 21:522
Content type: Study protocol Published on: 7 August 2020
- View Full Text
- View PDF
Acceptability and preliminary effectiveness of a single-arm 12-week digital behavioral health intervention in patients with knee osteoarthritis
Digital health interventions may improve osteoarthritis (OA) management. This study evaluated the acceptability and preliminary effectiveness of a multimodal digital nutrition, exercise, and mindfulness interv...
Authors: Kristine Godziuk, Carla M. Prado, Maira Quintanilha and Mary Forhan
Citation: BMC Musculoskeletal Disorders 2023 24:129
Content type: Research Published on: 17 February 2023
- View Full Text
- View PDF
Economic evaluation of access to musculoskeletal care: the case of waiting for total knee arthroplasty
The projected demand for total knee arthroplasty is staggering. At its root, the solution involves increasing supply or decreasing demand. Other developed nations have used rationing and wait times to distribu...
Authors: Richard C Mather III, Kevin T Hug, Lori A Orlando, Tyler Steven Watters, Lane Koenig, Ryan M Nunley and Michael P Bolognesi
Citation: BMC Musculoskeletal Disorders 2014 15:22
Content type: Research article Published on: 18 January 2014
- View Full Text
- View PDF
The reliability and minimal detectable change of Timed Up and Go test in individuals with grade 1 – 3 knee osteoarthritis
The Timed Up and Go (TUG) test is quick and easy tests to assess patients’ functional mobility. However, its reliability in individuals with knee osteoarthritis (OA) has not been well established. The aims of ...
Authors: Ahmad Alghadir, Shahnawaz Anwer and Jean-Michel Brismée
Citation: BMC Musculoskeletal Disorders 2015 16:174
Content type: Research article Published on: 30 July 2015
- View Full Text
- View PDF
Comparison of weight bearing functional exercise and non-weight bearing quadriceps strengthening exercise on pain and function for people with knee osteoarthritis and obesity: protocol for the TARGET randomised controlled trial
Clinical guidelines recommend exercise as a core treatment for individuals with knee osteoarthritis (OA). However, the best type of exercise for clinical benefits is not clear, particularly in different OA sub...
Authors: Kim L. Bennell, Rachel K. Nelligan, Alexander J. Kimp, Tim V. Wrigley, Ben Metcalf, Jessica Kasza, Paul W. Hodges and Rana S. Hinman
Citation: BMC Musculoskeletal Disorders 2019 20:291
Content type: Study protocol Published on: 18 June 2019
- View Full Text
- View PDF